Noelle CALLIZOT

En résumé

Entreprises

• Neuro-sys - CSO @Neuro/Sys (co-founder) - Pharmaceutical development director @Alzprotect SAS

  2013 - maintenant Scientific and/or Executive board member :
  * NEURO-SYS (co-founder), NEURADOM (co-founder), NEURON REHAB (co-founder), ALZPROTECT, INFLECTIS, NEURALIA-NEUTRACEUTICALS (co-founder) ...
  
  
  AFM-Téléthon :
  * Permanent Member of AFM-Téléthon scientific board (Paris)
  * Co-President of the "PHARMACOLOGICAL THERAPY AND TRANSLATIONAL RESEARCH"​ Commission
  
  Expertise:
  * Rare diseases (Neuro-muscular orphan diseases)
  * Drug discovery and development from medicinal plants. Specialist of neuro-development of plant extract.
  * Scientific adviser :
  - Expert in drug development and drug discovery for neurocompounds.
  - Specialist in neurodegenerative diseases (Alzheimer, Parkinson's disease, Amyotrophic lateral sclerosis, demyelinating diseases).
  - Drug discovery development plan design (pre-clinical testing on in vitro and in vivo models).
  Specialist in vitro/vivo models of neurodegenerative diseases (AD, PD, ALS...)
  Mode of action investigations, primary targets, signalisation pathways study designs.
  Preclinical (Pharmacology, PK/PD and ADME) expert. Early clinical design (PoC studies).
  
  Expertise:
  * CTX / IND, regulatory requirements and submission knowledge.
  * Investigator brochure (IB), IMPD
  * ODD submission (FDA/EMA) in neuro-indication
  * patents, abstracts, publications and communications, posters...
  * research projects, protocols

• Neuron experts - CSO - Head of research

  2009 - 2013 Neuron Experts (CRO).
  Head of Research and development, cell models development of AD, PD, ALS, HD..., development of new protocols of primary cell cultures.
  Writing of neurological research projects and protocols for biotechs and big pharmas. CTX / IND, regulatory requirements and submission knowledge., Writing of patents, abstracts, publications and communications, posters, external presentations.
  Business Development director

• NeuroPharmacologist (PharmD, PhD) - Consultant

  2009 - 2009 Consultant for big pharma, biotech and academia
  -Expertise in the pharmaceutical development (preclinical and clinical) for neuroprotective and neurotrophic drugs of neurodegenerative diseases (ALS, PD, AD, neuropathies…).
  -Key opinion leader network in neurology areas.
  -Expertise in pre-clinical models of neurodegenerative diseases:
  -Animal facilities expertise (rodents and transgenic animals)
  -Writing of neurological research projects and protocols for biotechs and big pharmas. CTX / IND, regulatory requirements and submission knowledge., Writing of patents, abstracts, publications and communications, posters, external presentations.
  -Business development advices (for “out and in licensing” strategies)

• Phytopharm - Director of Neuropharmacology

  2005 - 2009 Head of NeuroPharmacology, New opportunity manager
  -Responsibility of staff people (2 PhD, 1 research assistant).
  -In charge of pre-clinical vitro and vivo pharmacology programs for 2 compounds under development for Alzheimer (Ph IIa) and ALS diseases (PhI).
  -Dealing with external CRO and academia.
  -New opportunities manager (identification, evaluation and searches of new research programs in accordance with business strategy and marketing, advice for new indications for compounds under development)

• Neuro3D SA - Scientific and business development director of Neurofit (department of Neuro3D SA) (sales: 1.5 M€)

  2003 - 2005 -Management of 15 staff (PhD, research assistant, animal care and administrative staff),
  -Budget setting up
  -Management of the merge between Neuro3D SA and Neurofit SA.

• Neurofit SA (co-founder) - Scientific director and Business Development director

  1999 - 2003 Managment of 15 staff (PhD, research assistant, administrative staff)
  - Budget setting up
  - Business activities (sales: 1.5 M€)
  - Writing of neurological research projects and protocols for biotechs and big pharmas.
  - Advices in the pharmaceutical development of new drugs in neurodegenerative diseases.
  - CTX or IND submission writing
  -Coordination of research and development programs and contracted projects for in vivo and in vitro departments, preparation of reports and cost estimates for diverse industrial/academic partners
  - Development, setting up and validation of in vivo (rats and mice and transgenic/KO mice) and in vitro (primary cell cultures) test systems.
  - Writing of patents, abstracts, publications and communications.
  - Commercial contacts with the pharmaceutical industries, follow up of client contacts, external presentations of company activities to pharmaceutical and biotech companies

Formations

• Université Strasbourg 1 Louis Pasteur ULP

  Illkirch, Strasbourg 1992 - 1998 Doctorat in Pharmacy

• Université Strasbourg 1 Louis Pasteur

  Strasbourg 1992 - 2001 Animal models of neurodegenerative diseases (Parkinson and induced neuropathies)

Réseau

• Carmine ARABIA

• Emmanuel GUTMAN

• Emmanuelle LADET

• Emmy KENNETH

• Frederic BRETON

• Guillaume BOLLOT

• Philippe VERQUIERE

• Pierre-Yves GOUIFFES

• Romain MICHELON

• Stéphane GUERIN