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Claire PERRUISSEAU-CARRIER

En résumé

Always in search of challenging projects to make a difference.
Innovative and creative scientist interested in stem cells, translational medicine research, communication and project management.
Over 5 years research experience in the biotech start-up, pharmaceutical and nutritional industry. I have been responsible of several research projects, initiating collaborations, managing trainees, presenting in international conferences.
Specialties: Stem cells, 2D and 3D cell culture, molecular biology.

Mes compétences :
Bio
Biochemistry
Bioinformatics
Biology
Biotechnology
Economy
English
Fermentation
Management
Molecular biology
Production
Purification
Transfection
Statistiques
Communication
Gestion de projet
Biotechnologies
Santé

Entreprises

  • Nestlé Institute of Health and Sciences - Research Assistant - Cell biology - Stem cells

    2014 - 2015 > Combined in vitro & in vivo iPSCs pancreatic differentiation.

    > Aging impact on mice skeletal muscle satellite cells niche.

  • University Lyon 1 - Research assistant

    2009 - 2012 Neuronal commitment of umbilical cord mesenchymal stem cells for brain regenerative medicine.
    Human stem cells & neurosciences:
    = Process of human umbilical cord and cord blood
    = Isolation of human umbilical cord mesenchymal stem cells (hUC-MSC)
    = Expansion of hUC-MSC:
    - in classical serum contening culture conditions
    - in challenging serum-free culture conditions
    = Establishment of a protocol for the commitment of hUC-MSC to neuronal lineages

    Development of clinical-friendly protocols for translational and clinical research in stem cells and regenerative medicine.

  • Merck Serono, Geneva, Switzerland - One-year trainee in research in the Protein and Cell Sciences department

    2008 - 2009 Modulation of HEK293 cellular pathways for the production of
    recombinant proteins in mammalian cells, using miRNAs.
    Modelisation of the cellular pathways to be targeted by the miRNA of
    choice.
    Establishment of a miRNA expression profiling in HEK293 cells.
    Establishment of cDNA and miRNA transfection protocols in a 96-well
    plate format.
    Development and optimization of methods for the evaluation of miRNA
    impact on target mRNA expression level.
    Optimization of ELISA protocol in order to evaluate the impact of the
    transfection of miRNAs on recombinant monoclonal antibody production
    level.

  • Ste Justine Hospital, Montreal, Canada - 8-month trainee in Molecular Biology at the Endocrinology Research Center

    2005 - 2006 Study of the role of methylation in TTF-2 gene expression in SK Hep1
    cells.
    Bioinformatic characterization of the TTF-2 promoter
    Study of differential methylation of TTF-2 promoter CpG sites among cell
    lines
    Influence of 5-aza-dC treatment on TTF-2 expression in SK Hep1 cell line

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